Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45211 | 0.81 | LMNA (0.39) | LMNASMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL12772282 | 0.72 | CHRM1 (0.51) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL8911623 | 0.71 | ALDH1A3 (0.45) | MAPK1HTTKMT2AMEN1MAPT | |
| SCHEMBL12908043 | 0.70 | ALDH1A1 (0.58) | LMNAMAPK1HTTKMT2AMEN1 | |
| SCHEMBL8910752 | 0.70 | TRPV1 (0.44) | LMNASMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL13419187 | 0.69 | ALDH1A1 (0.61) | LMNAMAPK1HTTKMT2AMEN1 | |
| SCHEMBL8910816 | 0.68 | BCHE (0.42) | LMNASMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL3136809 | 0.68 | ALDH1A1 (0.46) | LMNASMN1; SMN2MAPK1HTTKMT2A | |
| SCHEMBL12082638 | 0.67 | MAPT (0.64) | LMNASMN1; SMN2MAPK1HTTMAPT | |
| SCHEMBL20860985 | 0.67 | GRIN2D (0.55) | SMN1; SMN2MAPK1HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625046-A | Hydroxyl projecting groups for organic synthesis | KING'S COLLEGE LONDON (GB) | 1997-04-29 | — | — | US | disclosed |
| US-5436331-A | Etherification with N-aryl-4-alkoxy-1,2,5,6-tetrahydropyidine | KINGS COLLEGE LONDON (GB) | 1995-07-25 | — | — | US | disclosed |
| EP-0298982-B1 | PROTECTING GROUPS FOR ORGANIC SYNTHESIS | KING'S COLLEGE LONDON (GB) | 1991-08-28 | — | — | EP | disclosed |