Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21623 | 0.80 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL7516695 | 0.77 | CHRNA7 (0.42) | ALDH1A1SMN1; SMN2KDM4ELMNAPOLB | |
| SCHEMBL14689798 | 0.70 | HSD17B10 (0.53) | ALDH1A1SMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL8910067 | 0.70 | LMNA (0.36) | ALDH1A1SMN1; SMN2KDM4EGAALMNA | |
| SCHEMBL30337113 | 0.68 | MEN1 (0.44) | TRPV1ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL4793090 | 0.67 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL4565387 | 0.67 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL1361317 | 0.67 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2KDM4EGAATSHR | |
| SCHEMBL4072195 | 0.67 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2KDM4ETDP1GAA | |
| SCHEMBL29500305 | 0.67 | DRD1 (0.57) | ALDH1A1SMN1; SMN2KDM4EGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625046-A | Hydroxyl projecting groups for organic synthesis | KING'S COLLEGE LONDON (GB) | 1997-04-29 | — | — | US | disclosed |
| US-5436331-A | Etherification with N-aryl-4-alkoxy-1,2,5,6-tetrahydropyidine | KINGS COLLEGE LONDON (GB) | 1995-07-25 | — | — | US | disclosed |
| EP-0298982-B1 | PROTECTING GROUPS FOR ORGANIC SYNTHESIS | KING'S COLLEGE LONDON (GB) | 1991-08-28 | — | — | EP | disclosed |