Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | HTR7 | P34969 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8910776 | 0.91 | HTR7 (0.42) | DRD4SIGMAR1DRD2HTR7DRD3 | |
| SCHEMBL8910318 | 0.84 | HTR7 (0.43) | DRD4SIGMAR1DRD2HTR7L3MBTL1 | |
| SCHEMBL8910772 | 0.74 | DRD4 (0.37) | DRD4DRD2HTR7KDM4EMEN1 | |
| SCHEMBL8910314 | 0.67 | DRD4 (0.41) | DRD4HTR7KDM4EGAAMEN1 | |
| SCHEMBL13079491 | 0.62 | KDM4E (0.78) | DRD4SIGMAR1DRD2DRD3DRD5 | |
| SCHEMBL588149 | 0.60 | DRD4 (1.00) | DRD4SIGMAR1DRD2HTR7L3MBTL1 | |
| SCHEMBL1319781 | 0.59 | SIGMAR1 (0.46) | SIGMAR1HTR7MEN1MAPTKMT2A | |
| SCHEMBL29715804 | 0.59 | KDM4E (0.71) | DRD4SIGMAR1DRD2DRD3DRD5 | |
| SCHEMBL3453669 | 0.58 | DRD2 (1.00) | DRD4SIGMAR1DRD2DRD3MEN1 | |
| SCHEMBL7606468 | 0.58 | MAPT (0.57) | DRD4SIGMAR1DRD2L3MBTL1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |