Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780579 | 0.81 | LTA4H (0.44) | CHRNA7SIGMAR1DRD2LMNAMAPT | |
| SCHEMBL8911501 | 0.77 | CHRNA7 (0.48) | CHRNA7SIGMAR1DRD2LMNAMAPT | |
| SCHEMBL8910752 | 0.77 | TRPV1 (0.44) | LMNAMAPK1HSD17B10MEN1KMT2A | |
| SCHEMBL17888252 | 0.76 | CHRNA7 (0.46) | CHRNA7SIGMAR1DRD2LMNAMAPT | |
| SCHEMBL16049287 | 0.73 | HTT (0.36) | DRD2LMNAMAPTMAPK1POLB | |
| SCHEMBL21078124 | 0.72 | CHRNA7 (0.41) | CHRNA7SIGMAR1DRD2LMNAMAPT | |
| SCHEMBL11834602 | 0.72 | CHRNA7 (0.41) | CHRNA7SIGMAR1DRD2LMNAMAPT | |
| SCHEMBL13945550 | 0.71 | ALDH1A1 (0.42) | CHRNA7SIGMAR1DRD2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL1596638 | 0.70 | DRD4 (0.50) | SIGMAR1DRD2MAPTALOX15MEN1 | |
| SCHEMBL10263391 | 0.67 | LMNA (0.58) | SIGMAR1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786462-B1 | DC107 derivatives | KYOWA HAKKO KOGYO KK (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-5733924-A | BACTERICIDES AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0786462-A1 | DC107 DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |