Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14689798 | 0.81 | HSD17B10 (0.53) | SMN1; SMN2ALDH1A1HSD17B10KDM4ETDP1 | |
| SCHEMBL8910752 | 0.80 | TRPV1 (0.44) | SMN1; SMN2ALDH1A1HSD17B10KDM4ETDP1 | |
| SCHEMBL1057317 | 0.80 | ADRB1 (0.52) | SMN1; SMN2ALDH1A1KDM4EGAATSHR | |
| SCHEMBL1361317 | 0.76 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1HSD17B10KDM4EGAA | |
| SCHEMBL668861 | 0.75 | HTR7 (0.40) | SMN1; SMN2ALDH1A1KDM4ETDP1TSHR | |
| SCHEMBL23161511 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1HSD17B10KDM4ETDP1 | |
| SCHEMBL3042980 | 0.74 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1HSD17B10KDM4ETDP1 | |
| SCHEMBL13941994 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1HSD17B10KDM4ETDP1 | |
| SCHEMBL21624 | 0.74 | NOTUM (0.49) | SMN1; SMN2ALDH1A1HSD17B10KDM4ETDP1 | |
| SCHEMBL8911501 | 0.73 | CHRNA7 (0.48) | SMN1; SMN2ALDH1A1HSD17B10KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1052 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606338-A | 6' -cyano modified locked nucleosides, nucleotides and nucleic acid polymers | 中国人民解放军军事科学院军事医学研究院 | 2023-08-18 | — | — | CN | claimed |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) | 2023-06-22 | — | — | US | claimed |
| EP-3119789-B1 | BICYCLIC CARBOCYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | IONIS PHARMACEUTICALS INC (US) | 2020-04-22 | — | — | EP | claimed |
| US-10287313-B2 | RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2019-05-14 | — | — | US | claimed |
| EP-2748176-B1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2019-04-17 | — | — | EP | claimed |
| EP-3323414-A1 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2018-05-23 | — | — | EP | claimed |
| EP-2850092-B1 | TRICYCLIC NUCLEIC ACID ANALOGS | IONIS PHARMACEUTICALS INC (US) | 2017-03-01 | — | — | EP | claimed |
| US-20160340382-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2016-11-24 | — | — | US | claimed |
| EP-2727915-B1 | Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof | CONCERT PHARMACEUTICALS INC (US) | 2016-04-13 | — | — | EP | claimed |
| EP-2334692-B1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | UNIV MCGILL (CA) | 2016-04-13 | — | — | EP | claimed |
| US-6949639-B1 | Oligonucleotide labeling reactants and their use | WALLAC OY (FI) | 2005-09-27 | — | — | US | claimed |
| US-20040260080-A1 | Oligonucleotide labeling reactants and their use | HOVINEN JARI (FI) | 2004-12-23 | — | — | US | claimed |
| WO-2004064745-A2 | METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES | AUSPEX PHARMACEUTICALS, INC. (US) | 2004-08-05 | — | — | WO | claimed |
| EP-1152010-A2 | Oligonucleotide labeling reactants and their use | WALLAC OY (FI) | 2001-11-07 | — | — | EP | claimed |
| US-5789562-A | STABLE HYBRIDIZATION COMPLEXES WITH NUCLEI ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | claimed |
| US-5721350-A | Deuterated nucleosides | CHATTOPADHYAYA JYOTI (SE) | 1998-02-24 | — | — | US | claimed |
| EP-0710667-A2 | Modified oligonucleotides, their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-08 | — | — | EP | claimed |
| EP-0680969-A2 | Modified oligonucleotides, their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-08 | — | — | EP | claimed |
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10287313-B2 | RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays | EFTUD2, RNMT, NSUN2 | SMN1; SMN2 905/4885ALDH1A1 199/4885HSD17B10 1459/4885 |
| US-20040260080-A1 | Oligonucleotide labeling reactants and their use | SSU72, LIG4, NSUN2 | SMN1; SMN2 1570/4885ALDH1A1 1426/4885HSD17B10 3345/4885 |
| US-20160340382-A1 | RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS | EFTUD2, RNMT, RNGTT | SMN1; SMN2 1087/4885ALDH1A1 212/4885HSD17B10 1594/4885 |
| US-20230192751-A1 | METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES | POLN, POLRMT, POLI | SMN1; SMN2 1452/4885ALDH1A1 4284/4885HSD17B10 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.