Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | GRN | P28799 | 7/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 7/20 | 0.37 |
| ▸ | PLOD2 | O00469 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.36 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.36 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912055 | 0.89 | RAB9A (0.39) | RAB9ATPMTGRNSORT1PLOD2 | |
| SCHEMBL8911235 | 0.87 | RAB9A (0.38) | RAB9ATPMTGRNSORT1PLOD2 | |
| SCHEMBL8912553 | 0.84 | RAB9A (0.36) | RAB9ATPMTGRNSORT1PLOD2 | |
| SCHEMBL8911024 | 0.83 | CES2 (0.46) | PLOD2CYP3A4GAAPLOD3PLOD1 | |
| SCHEMBL8910998 | 0.80 | PLOD2 (0.41) | RAB9APLOD2MEN1KMT2APLOD3 | |
| SCHEMBL8911395 | 0.78 | RAB9A (0.41) | RAB9ATPMTGRNSORT1PLOD2 | |
| SCHEMBL8912050 | 0.78 | GPR139 (0.36) | RAB9AGRNSORT1PLOD2MEN1 | |
| SCHEMBL8913602 | 0.75 | RAB9A (0.39) | RAB9ATPMTGRNSORT1PLOD2 | |
| SCHEMBL8911624 | 0.74 | RAB9A (0.38) | RAB9ATPMTGRNSORT1PLOD2 | |
| SCHEMBL8910631 | 0.71 | GPR139 (0.36) | RAB9APLOD2PLOD3PLOD1ERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| EP-0317275-B1 | Control of ectoparasites | BRITISH TECH GROUP USA (US) | 1994-08-03 | — | — | EP | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |
| EP-0317275-A2 | Control of ectoparasites | BRITISH TECHNOLOGY GROUP USA INC. (US) | 1989-05-24 | — | — | EP | disclosed |