Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482148 | 0.83 | LTB4R2 (0.36) | LTB4R2AGTR1PKMTSHR | |
| SCHEMBL8910135 | 0.80 | PTPN1 (0.32) | PTPN1 | |
| SCHEMBL8910129 | 0.79 | S1PR1 (0.38) | CTSBCTSSPTPN1 | |
| SCHEMBL8911282 | 0.77 | LTB4R2 (0.34) | LTB4R2AGTR1PKMTSHR | |
| SCHEMBL8806815 | 0.76 | ACHE (0.34) | LTB4R2AGTR1PKM | |
| SCHEMBL8486942 | 0.75 | LTB4R2 (0.35) | LTB4R2AGTR1PKMTSHR | |
| SCHEMBL2515 | 0.75 | LTB4R2 (0.49) | LTB4R2AGTR1 | |
| SCHEMBL8807370 | 0.73 | AGTR1 (0.41) | LTB4R2AGTR1CTSLCTSBCTSS | |
| SCHEMBL8809681 | 0.73 | AGTR1 (0.41) | LTB4R2AGTR1PKM | |
| SCHEMBL8485848 | 0.72 | LTB4R2 (0.41) | LTB4R2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620998-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-04-15 | — | — | US | disclosed |
| US-5506240-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |