SCHEMBL891138

SCHEMBL891138

Cc1ccc(S(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.80
SMN1; SMN2 Q16637 2/20 0.70
HTT P42858 2/20 0.70
HTR6 P50406 2/20 0.70
ALDH1A1 P00352 3/20 0.57
MAPT P10636 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
POLB P06746 1/20 0.57
CA12 O43570 3/20 0.55
CA9 Q16790 3/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
BCHE P06276 1/20 0.55
ACHE P22303 1/20 0.55
RAPGEF4 Q8WZA2 1/20 0.54
CA3 P07451 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12336795 0.93 GAA (0.70) GAASMN1; SMN2HTTHTR6ALDH1A1
SCHEMBL27713195 0.93 GAA (0.70) GAASMN1; SMN2HTTHTR6ALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL6912665 0.92 HTR6 (0.74) GAASMN1; SMN2HTTHTR6ALDH1A1
(Phenylsulfonyl)Benzene SCHEMBL28475578 0.89 GAA (0.64) GAASMN1; SMN2HTTHTR6ALDH1A1
SCHEMBL170033 0.89 GAA (1.00) GAASMN1; SMN2HTTHTR6ALDH1A1
SCHEMBL10067072 0.89 GAA (1.00) GAASMN1; SMN2HTTHTR6ALDH1A1
SCHEMBL4400955 0.89 GAA (1.00) GAASMN1; SMN2HTTHTR6ALDH1A1
SCHEMBL28479802 0.89 GAA (0.70) GAASMN1; SMN2HTTHTR6ALDH1A1
SCHEMBL13917647 0.88 GAA (0.61) GAASMN1; SMN2HTTHTR6ALDH1A1
Water SCHEMBL9619041 0.87 GAA (0.94) GAASMN1; SMN2HTTALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 359 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115084655-A Electrolyte, preparation method thereof and lithium metal battery containing electrolyte 蜂巢能源科技(无锡)有限公司 2022-09-20 CN claimed
US-9650330-B2 Process for the synthesis of aryl sulfones COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2017-05-16 US claimed
US-9505255-B2 Thermal imaging members and methods ZINK HOLDINGS LLC 2016-11-29 US claimed
US-20160304447-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2016-10-20 US claimed
WO-2015087352-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2015-06-18 WO claimed
US-20150119237-A1 THERMAL IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. (US) 2015-04-30 US claimed
CN-102203066-A Novel dyes and use thereof in imaging members and methods ZINK IMAGING INC 2011-09-28 CN claimed
US-20110080458-A1 NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, INC. 2011-04-07 US claimed
US-7829497-B2 Thermal imaging members and methods ZINK IMAGING, INC. (US) 2010-11-09 US claimed
US-7704667-B2 Dyes and use thereof in imaging members and methods ZINK IMAGING, INC. (US) 2010-04-27 US claimed
JP-2008544877-A 2008-12-11 JP claimed
CN-101302176-A Method for preparing p-toluenesulfonic acid by gas-phase sulphonation of toluol with sulfur trioxide NANJING JINGMEI CHEMICAL CO LT (CN) 2008-11-12 CN claimed
US-20080187866-A1 NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS ZINK IMAGING, LLC 2008-08-07 US claimed
EP-1879750-A2 THERMAL IMAGING MEMBERS AND METHODS Zink Imaging, LLC (US) 2008-01-23 EP claimed
US-20060293185-A1 Thermal imaging members and methods ZINK IMAGING, LLC 2006-12-28 US claimed
WO-2006124560-A2 THERMAL IMAGING MEMBERS AND METHODS ZINK IMAGING, LLC (US) 2006-11-23 WO claimed
US-20030162995-A1 Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases DOW GLOBAL TECHNOLOGIES LLC 2003-08-28 US claimed
EP-1255728-A1 INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES Enichem S.p.A. (IT) 2002-11-13 EP claimed
WO-2001056977-A1 INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES ENICHEM S.P.A. (IT) 2001-08-09 WO claimed
US-4968758-A MOLODING MATERIALS WITH EXCELLENT HEAT, SOLVENT, AND STRESS-CRACK RESISTANCE AMOCO CORPORATION (US) 1990-11-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080187866-A1 NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS CACYBP, KLHDC2, ZKSCAN2 GAA 1970/4885SMN1; SMN2 4599/4885HTT 2335/4885
US-20160304447-A1 A PROCESS FOR THE SYNTHESIS OF ARYL SULFONES ARSA, TPST2, STS GAA 423/4885SMN1; SMN2 1701/4885HTT 1264/4885
US-20150119237-A1 THERMAL IMAGING MEMBERS AND METHODS HEATR1, HEATR6, HSPBP1 GAA 499/4885SMN1; SMN2 4196/4885HTT 623/4885
US-20110080458-A1 NOVEL DYES AND USE THEREOF IN IMAGING MEMBERS AND METHODS CACYBP, KLHDC2, ZKSCAN2 GAA 1970/4885SMN1; SMN2 4599/4885HTT 2335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.