Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 15/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16808018 | 0.84 | P2RX4 (0.49) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL20353763 | 0.76 | LMNA (0.42) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL11088295 | 0.71 | P2RX4 (0.43) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL19733503 | 0.70 | HSD17B3 (0.39) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL627990 | 0.70 | MAOA (0.52) | LMNA | |
| SCHEMBL9179488 | 0.70 | HPGD (0.42) | LMNATSHRSMN1; SMN2 | |
| SCHEMBL9036500 | 0.70 | MEN1 (0.47) | TSHRSMN1; SMN2 | |
| SCHEMBL11739419 | 0.70 | P2RX4 (0.48) | P2RX4P2RX1P2RX3SMN1; SMN2NPSR1 | |
| SCHEMBL3453648 | 0.69 | LMNA (0.36) | LMNATSHRMAPK1SCN4ASCN5A | |
| SCHEMBL30466762 | 0.68 | LMNA (0.48) | LMNATSHRMAPK1SCN4ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024053-B2 | Compound obtained by dimerizing with light irradiation, a compound containing a group having lyophilicity, and a compound containing a group having liquid-repellency | JOLED INC. (JP) | 2015-05-05 | — | — | US | disclosed |
| US-8847211-B2 | Device, thin film transistor, method for manufacturing the device and method for manufacturing the thin film transistor | PANASONIC CORPORATION (JP) | 2014-09-30 | — | — | US | disclosed |
| US-7875467-B2 | Chemiluminescence; quantitative analysis of macromolecules; complexing sample to acridinium compound, labels for improving sensitivity of immunoassays, 2',6'-dimethyl-4'-N-succinimidyloxycaproyl-amidocarbonylphenyl-N10-2,7-tris[O-methoxyhexa(ethylene) glycol-sulfonamidylpropyl]-acridinium-9-carboxylate | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2011-01-25 | — | — | US | disclosed |
| US-20080305557-A1 | Novel Applications of Acridinium Compounds and Derivatives in Homogeneous Assays | SIEMENS MEDICAL SOLUTIONS DIAGNOSTICS (US) | 2008-12-11 | — | — | US | disclosed |
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0691962-A1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0363212-B1 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5204348-A | Quinoline derivatives | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |
| US-3992370-A | 1,1-Dichloro-1a,1b-dihydrodibenzo(b,f)cycloprop(d)azepine-6(1H)-carboxaldehyde | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-11-16 | — | — | US | disclosed |