Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23520298 | 0.77 | ALDH1A1 (0.36) | LMNAALDH1A1GAAMCL1PAX8 | |
| SCHEMBL17275723 | 0.75 | ALDH1A1 (0.50) | LMNAALDH1A1GAAMCL1PAX8 | |
| SCHEMBL26327450 | 0.75 | KMT2A (0.42) | LMNAALDH1A1GAAMCL1PAX8 | |
| SCHEMBL25682366 | 0.73 | GAA (0.48) | LMNAALDH1A1GAAMCL1PAX8 | |
| SCHEMBL28060229 | 0.71 | GAA (0.37) | LMNAALDH1A1GAAMCL1PAX8 | |
| SCHEMBL10345602 | 0.66 | NR1H3 (0.35) | LMNAALDH1A1GAAMCL1PAX8 | |
| SCHEMBL15907068 | 0.65 | ALDH1A1 (0.39) | LMNAALDH1A1GAAMCL1PAX8 | |
| SCHEMBL2393621 | 0.65 | LMNA (0.57) | LMNAALDH1A1GAAMCL1PAX8 | |
| SCHEMBL29565250 | 0.64 | ALDH1A1 (0.47) | LMNAALDH1A1GAAMCL1PAX8 | |
| SCHEMBL21726115 | 0.64 | MAPT (0.40) | LMNAALDH1A1GAAMCL1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3087094-B1 | BETA-HAIRPIN PEPTIDOMIMETICS AS SELECTIVE ELASTASE INHIBITORS | POLYPHOR AG (CH) | 2022-06-01 | — | — | EP | disclosed |
| EP-0489655-B1 | Indolino-spiro-benzoxazine photochromic compounds and process for their preparation | ESSILOR INT (FR) | 1997-05-28 | — | — | EP | disclosed |
| EP-0402228-B1 | Indolino-spiro-oxazine photochromic compounds having a five-membered ring, process for their preparation and photochromic compositions and materials containing them | ESSILOR INT (FR) | 1996-01-03 | — | — | EP | disclosed |
| EP-0407237-B1 | Indolino-spiro-oxazine photochromic compounds, process for their preparation and photochromic compositions and materials containing them | ESSILOR INT (FR) | 1995-11-29 | — | — | EP | disclosed |
| US-5233038-A | PHOTOCHRONIC COMPOUNDS OF THE INDOLINO-SPIRO-BENZOXAZINE TYPE | ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) | 1993-08-03 | — | — | US | disclosed |
| EP-0489655-A1 | Indoline-spiro-benzoxazine photochromic compounds and process for their preparation | ESSILOR INTERNATIONAL Compagnie Générale d'Optique (FR) | 1992-06-10 | — | — | EP | disclosed |
| EP-0407237-A2 | Indolino-spiro-oxazine photochromic compounds, process for their preparation and photochromic compositions and materials containing them | ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) | 1991-01-09 | — | — | EP | disclosed |
| EP-0402228-A2 | Indolino-spiro-oxazine photochromic compounds having a five-membered ring, process for their preparation and photochromic compositions and materials containing them | ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) | 1990-12-12 | — | — | EP | disclosed |
| US-4542224-A | Process for preparing cationic methine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1985-09-17 | — | — | US | disclosed |
| EP-0092698-B1 | PROCESS FOR THE PREPARATION OF CATIONIC METHINE DYES | BAYER AG (DE) | 1985-06-26 | — | — | EP | disclosed |
| EP-0092698-A1 | Process for the preparation of cationic methine dyes | BAYER AG (DE) | 1983-11-02 | — | — | EP | disclosed |