Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12659492 | 0.81 | MAPT (0.35) | MAPTLMNASMN1; SMN2HTTTDP1 | |
| SCHEMBL5645606 | 0.80 | MAPT (0.35) | MAPTLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7936515 | 0.79 | KEAP1 (0.42) | MAPTKMT2AALDH1A1 | |
| SCHEMBL7479868 | 0.79 | MEN1 (0.40) | MAPTLMNASMN1; SMN2HTTKMT2A | |
| SCHEMBL1845080 | 0.79 | KEAP1 (0.38) | MAPTLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL5649476 | 0.79 | RAB9A (0.39) | MAPTSMN1; SMN2TDP1KMT2AALDH1A1 | |
| SCHEMBL14302089 | 0.77 | CNR2 (0.32) | MAPTSMN1; SMN2HTT | |
| SCHEMBL6480424 | 0.77 | SLC2A1 (0.32) | LMNAEDNRBEDNRAHTTKMT2A | |
| SCHEMBL9928123 | 0.76 | BRAF (0.35) | MAPTLMNASMN1; SMN2EDNRBEDNRA | |
| SCHEMBL7115389 | 0.76 | KMT2A (0.36) | MAPTLMNASMN1; SMN2EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722076-B2 | Photochrome- or near IR dye-coupled polymeric matrices for medical articles | SURMODICS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-8722076-B2 | Photochrome- or near IR dye-coupled polymeric matrices for medical articles | SURMODICS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | BANK OF MONTREAL, AS COLLATERAL AGENT | 2012-04-05 | — | — | US | disclosed |
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | BANK OF MONTREAL, AS COLLATERAL AGENT | 2012-04-05 | — | — | US | disclosed |
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | BANK OF MONTREAL, AS COLLATERAL AGENT | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120082713-A1 | PHOTOCHROME- OR NEAR IR DYE-COUPLED POLYMERIC MATRICES FOR MEDICAL ARTICLES | IK, PIR, PLOD1 | MAPT 836/4885LMNA 2754/4885SMN1; SMN2 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.