SCHEMBL8911941

SCHEMBL8911941

CCOC(=O)c1c(OC)csc1NC(=O)[C@H](C)NC(=O)OCc1ccccc1.COc1csc2nc([C@H](C)NC(=O)OCc3ccccc3)oc(=O)c12

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8907957 0.78 PRKCZ (0.44) ATM
SCHEMBL8907102 0.76 CTSK (0.49) ATM
SCHEMBL8911363 0.74 ATM (0.53) ATM
SCHEMBL8911359 0.74 ATM (0.53) ATM
SCHEMBL8912215 0.73 ATM (0.53) ATM
SCHEMBL8912223 0.73 ATM (0.53) ATM
SCHEMBL8912049 0.71 ATM (0.53) ATM
SCHEMBL8912043 0.71 ATM (0.53) ATM
SCHEMBL8911899 0.70 ATM (0.52) ATM
SCHEMBL8911892 0.70 ATM (0.52) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0799230-A1 THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS SMITHKLINE BEECHAM PLC (GB) 1997-10-08 EP disclosed
WO-1996019482-A1 THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS SMITHKLINE BEECHAM PLC (GB) 1996-06-27 WO disclosed