Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LGMN | Q99538 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907102 | 0.82 | CTSK (0.49) | PTPN1CTSKHDAC6KDM4EALDH1A1 | |
| SCHEMBL8911941 | 0.78 | ATM (0.43) | ATM | |
| SCHEMBL8907299 | 0.78 | CTSK (0.48) | CTSKALDH1A1HTTMEN1KMT2A | |
| SCHEMBL12414363 | 0.76 | LMNA (0.49) | PTPN1KDM4EALDH1A1HTTMEN1 | |
| SCHEMBL8913629 | 0.74 | ALDH1A1 (0.57) | CTSKKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8907072 | 0.73 | CTSK (0.48) | CTSKALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8908693 | 0.73 | CTSK (0.48) | CTSKALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8913894 | 0.72 | MEN1 (0.48) | PRKCZCTSKKDM4EALDH1A1MEN1 | |
| SCHEMBL8911355 | 0.71 | CTSK (0.48) | CTSKALDH1A1HTTMEN1KMT2A | |
| SCHEMBL8912016 | 0.69 | CNR2 (0.52) | CTSKKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799230-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019482-A1 | THIENOXAZINONE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1996-06-27 | — | — | WO | disclosed |