Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912397 | 0.75 | P2RX7 (0.38) | MEN1CYP3A4MAPTHTTKMT2A | |
| SCHEMBL4541683 | 0.64 | KDM4E (0.41) | CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL8911974 | 0.63 | ALDH1A1 (0.30) | MAPTKMT2ANPSR1 | |
| SCHEMBL4654883 | 0.59 | MAPT (0.69) | MEN1MAPTKMT2ANPSR1 | |
| Acridine SCHEMBL28511403 | 0.59 | MAPT (0.71) | MEN1CYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL1512986 | 0.58 | MAPT (0.46) | MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL29689895 | 0.58 | MAPT (0.46) | MEN1CYP1A2CYP3A4CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL28651484 | 0.57 | MAPT (0.44) | MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL31391239 | 0.54 | MYC (0.63) | MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL23558663 | 0.53 | HSD11B1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608065-A | ADAMANTANEOSPIRO-HETEROAROMATIC PYRANS | OPTISCHE WERKE G. RODENSTOCK (DE) | 1997-03-04 | — | — | US | claimed |