SCHEMBL8912629

SCHEMBL8912629

O=C(CC(=O)C1(F)C(F)(F)C(F)C1(F)F)c1cc(Br)cc(Br)c1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8911800 0.91
SCHEMBL8912916 0.74 DDR1 (0.38)
SCHEMBL8912083 0.72 GPR139 (0.31)
SCHEMBL8910968 0.68 CES2 (0.39)
SCHEMBL5254952 0.67 GSK3B (0.41) GSK3B
SCHEMBL5055139 0.67 GSK3B (0.60) GSK3B
SCHEMBL8913481 0.65 PLOD2 (0.38)
SCHEMBL8912782 0.64 RAB9A (0.36)
SCHEMBL5873147 0.64 KMT2A (0.68) GSK3B
SCHEMBL8911919 0.64 PLOD2 (0.40) GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5618547-A ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES BRITISH TECHNOLOGY GROUP LIMITED (GB) 1997-04-08 US disclosed
US-4870109-A ANIMAL HUSBANDRY ELI LILLY AND COMPANY (US) 1989-09-26 US disclosed
EP-0317275-A2 Control of ectoparasites BRITISH TECHNOLOGY GROUP USA INC. (US) 1989-05-24 EP disclosed