Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 10/20 | 0.43 |
| ▸ | CASP5 | P51878 | 10/20 | 0.43 |
| ▸ | CASP4 | P49662 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | GALR1 | P47211 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891364 | 0.93 | CASP1 (0.49) | CASP1CASP5CASP4ALDH1A1LMNA | |
| SCHEMBL8912652 | 0.75 | CASP1 (0.58) | CASP1CASP5CASP4ALDH1A1LMNA | |
| SCHEMBL8892044 | 0.74 | CASP1 (0.50) | CASP1CASP5CASP4MAPT | |
| SCHEMBL7769859 | 0.73 | MAPT (0.60) | TSHRMAPTKDM4EUSP2MAPK1 | |
| SCHEMBL8893240 | 0.73 | RAD52 (0.46) | ALDH1A1LMNAMAPTKDM4EMAPK1 | |
| SCHEMBL10143607 | 0.69 | HRH4 (0.81) | HRH4CASP1CASP5CASP4LMNA | |
| SCHEMBL4845325 | 0.68 | KDM1A (0.47) | ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL10377525 | 0.67 | HRH4 (0.78) | HRH4CASP1CASP5CASP4LMNA | |
| SCHEMBL8890641 | 0.67 | ABCB1 (0.50) | ALDH1A1LMNAMAPTKDM4EMAPK1 | |
| SCHEMBL10848170 | 0.66 | CASP1 (0.75) | HRH4CASP1CASP5CASP4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |