Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160221 | 0.83 | KMT2A (0.33) | KMT2AALDH1A1 | |
| SCHEMBL6160923 | 0.82 | MAPT (0.32) | INMTMAPT | |
| SCHEMBL6158568 | 0.82 | HSD11B1 (0.37) | — | |
| SCHEMBL6159601 | 0.82 | ALDH1A1 (0.36) | KMT2AALDH1A1 | |
| SCHEMBL8913135 | 0.81 | KMT2A (0.31) | KMT2ATSHRBLM | |
| SCHEMBL8912155 | 0.81 | TSHR (0.34) | TSHR | |
| SCHEMBL27661365 | 0.80 | TSHR (0.38) | KMT2AALDH1A1MAPTTSHRBLM | |
| SCHEMBL25195440 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL6160033 | 0.75 | ALDH1A1 (0.34) | ALDH1A1MAPTHSD17B10 | |
| SCHEMBL8912293 | 0.74 | FPR3 (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |