SCHEMBL8913818

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8916066	0.82	ALDH1A1 (0.61)	ALDH1A1TSHRSMN1; SMN2KMT2AMAPT
	SCHEMBL27920869	0.77	SMN1; SMN2 (0.57)	CMA1ALDH1A1HSD17B10TSHRSMN1; SMN2
	SCHEMBL8925245	0.76	DRD3 (0.54)	ALDH1A1SMN1; SMN2KMT2A
	SCHEMBL8914746	0.76	CMA1 (0.46)	CMA1ALDH1A1HSD17B10TSHRSMN1; SMN2
	SCHEMBL8912484	0.76	CMA1 (0.55)	CMA1ALDH1A1HSD17B10GAATSHR
	SCHEMBL8913952	0.74	KMT2A (0.50)	ALDH1A1SMN1; SMN2KMT2AMAPTMEN1
	SCHEMBL29348950	0.74	HSD11B1 (0.42)	ALDH1A1SMN1; SMN2HPGDKDM4ELMNA
	SCHEMBL17221774	0.74	SMN1; SMN2 (0.42)	ALDH1A1SMN1; SMN2KMT2AMEN1LMNA
	SCHEMBL13504002	0.73	L3MBTL1 (0.54)	CMA1ALDH1A1TSHRKMT2AMAPT
	SCHEMBL8915807	0.72	CHKA (0.59)	ALDH1A1HSD17B10KMT2AKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.