Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.58 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.58 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.58 |
| ▸ | GABRP | O00591 | 2/20 | 0.58 |
| ▸ | GABRD | O14764 | 2/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.58 |
| ▸ | GABRE | P78334 | 2/20 | 0.58 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.58 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.58 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.58 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.58 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8914604 | 0.98 | GABRA1 (0.57) | GABRA1GABRR1GABRA5GABRB2GABRA4 | |
| SCHEMBL8305945 | 0.76 | GABRA1 (0.64) | GABRA1GABRR1GABRA5GABRB2GABRA4 | |
| SCHEMBL8915209 | 0.74 | GABRA1 (1.00) | GABRA1GABRR1GABRA5GABRB2GABRA4 | |
| Hydrochloric Acid SCHEMBL8622201 | 0.74 | GABRA1 (0.62) | GABRA1GABRR1GABRA5GABRB2GABRA4 | |
| SCHEMBL8644376 | 0.70 | GABRP (0.54) | GABRA1GABRA5GABRB2GABRA4GABRP | |
| Hydrochloric Acid SCHEMBL8914475 | 0.69 | GABRP (0.53) | GABRA1GABRA5GABRB2GABRA4GABRP | |
| SCHEMBL25724241 | 0.64 | RIPK1 (0.35) | — | |
| SCHEMBL29143590 | 0.64 | CES2 (0.39) | — | |
| SCHEMBL3536151 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL4873775 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618818-A | STIMULATE MUSCARINIC RECEPTORS IN CENTRAL NERVOUS SYSTEM | THE UNIVERSITY OF TOLEDO (US) | 1997-04-08 | — | — | US | disclosed |