Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | BRD2 | P25440 | 2/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.48 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853392 | 0.89 | MEN1 (0.53) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL7320101 | 0.88 | MEN1 (0.52) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL19066322 | 0.79 | RXFP1 (0.59) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL19066314 | 0.79 | MEN1 (0.65) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL5093687 | 0.79 | HPGD (0.54) | NPSR1GAAALDH1A1POLBRAB9A | |
| SCHEMBL19090458 | 0.75 | ALDH1A1 (0.55) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL9298051 | 0.73 | ALDH1A1 (0.47) | MEN1KMT2ANPSR1GAAALDH1A1 | |
| SCHEMBL11401591 | 0.72 | MEN1 (0.81) | MEN1KMT2AALDH1A1RXFP1POLB | |
| SCHEMBL23255226 | 0.71 | TSHR (0.56) | MEN1KMT2ANPSR1ALDH1A1RXFP1 | |
| SCHEMBL11394726 | 0.71 | MEN1 (0.80) | MEN1KMT2AALDH1A1RXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564461-B1 | THE USE OF ANTIBODIES TO TNF OR FRAGMENTS DERIVED THEREOF AND XANTHINE DERIVATIVES FOR COMBINATION THERAPY AND COMPOSITIONS THEREFOR | CELLTECH THERAPEUTICS LTD (GB) | 1997-01-02 | — | — | EP | claimed |