Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326042 | 0.91 | AGTR1 (0.78) | AGTR2AGTR1 | |
| SCHEMBL8913280 | 0.90 | AGTR1 (0.77) | AGTR2AGTR1 | |
| SCHEMBL8326770 | 0.89 | AGTR2 (0.66) | AGTR2AGTR1 | |
| SCHEMBL8913274 | 0.89 | AGTR2 (0.65) | AGTR2AGTR1 | |
| SCHEMBL462 | 0.89 | AGTR2 (0.80) | AGTR2AGTR1 | |
| SCHEMBL8719876 | 0.88 | AGTR1 (0.57) | AGTR2AGTR1 | |
| SCHEMBL8792974 | 0.86 | AGTR2 (0.70) | AGTR2AGTR1 | |
| SCHEMBL8913133 | 0.83 | ALDH1A1 (0.50) | AGTR2AGTR1 | |
| SCHEMBL8792660 | 0.83 | AGTR2 (0.70) | AGTR2AGTR1 | |
| SCHEMBL883 | 0.82 | AGTR1 (0.69) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665881-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE, ANGIOTENSIN II ANTAGONIST | THE GREEN CROSS CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0693478-A1 | Quinoline compounds | THE GREEN CROSS CORPORATION (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5478832-A | Angiotensin II antagonists; cardiovascular disorders | THE GREEN CROSS CORPORATION (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0569013-A1 | Quinoline compounds as angiotensin II antagonists | THE GREEN CROSS CORPORATION (JP) | 1993-11-10 | — | — | EP | disclosed |