Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | METAP2 | P50579 | 2/20 | 0.48 |
| ▸ | METAP1 | P53582 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28233 | 0.77 | KDM4E (0.53) | MAPTKDM4EHSP90AA1LMNAMETAP2 | |
| SCHEMBL8914359 | 0.77 | MAPT (0.49) | MAPTKDM4EHSP90AA1LMNAMETAP2 | |
| SCHEMBL7859708 | 0.75 | RAB9A (0.55) | MAPTKDM4ELMNARAB9ANPC1 | |
| SCHEMBL4386263 | 0.74 | KDM4E (0.72) | MAPTKDM4EHSP90AA1LMNAMETAP2 | |
| SCHEMBL28727740 | 0.73 | KDM4E (0.56) | MAPTKDM4EHSP90AA1LMNAMETAP2 | |
| SCHEMBL29353166 | 0.73 | KDM4E (0.56) | MAPTKDM4EHSP90AA1LMNAMETAP2 | |
| Hydrochloric Acid SCHEMBL27496748 | 0.72 | KDM4E (0.59) | MAPTKDM4EHSP90AA1LMNAMETAP2 | |
| SCHEMBL28698652 | 0.72 | MAPT (0.51) | MAPTKDM4EHSP90AA1LMNAMETAP2 | |
| SCHEMBL24179773 | 0.72 | LMNA (0.55) | MAPTKDM4EHSP90AA1LMNAMETAP2 | |
| SCHEMBL8008984 | 0.72 | ALDH1A1 (0.46) | KDM4ERAB9AL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633364-A | N4 -substituted 2'-deoxycytidine compounds, oligonucleotides including N4 -labeled 2'-deoxycytidines, and a process for making oligonucleotides with N-modified 2'-deoxycytidines | AMOCO CORPORATION (US) | 1997-05-27 | — | — | US | claimed |