Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915606 | 0.79 | RAB9A (0.69) | SMN1; SMN2ALDH1A1HSD17B10HPGDALOX15 | |
| SCHEMBL9213950 | 0.78 | PDE10A (0.41) | SMN1; SMN2ALDH1A1MAPK1LMNAKDM4E | |
| SCHEMBL8914486 | 0.77 | KDM4E (0.49) | SMN1; SMN2ALDH1A1HSD17B10MAPK1LMNA | |
| SCHEMBL5109272 | 0.75 | CYP3A4 (0.52) | ALDH1A1MAPTTP53 | |
| SCHEMBL8918377 | 0.75 | SIGMAR1 (0.42) | SMN1; SMN2ALDH1A1MAPK1LMNAKDM4E | |
| SCHEMBL8915212 | 0.75 | KDM4E (0.43) | SMN1; SMN2ALDH1A1MAPK1LMNAKDM4E | |
| SCHEMBL8914183 | 0.74 | GAA (0.50) | ALDH1A1KDM4EHPGDTSHRGAA | |
| SCHEMBL8914024 | 0.74 | L3MBTL1 (0.45) | ALDH1A1HSD17B10KDM4EHPGDGAA | |
| SCHEMBL9052359 | 0.74 | GRIN2B (0.43) | SMN1; SMN2ALDH1A1HSD17B10MAPK1LMNA | |
| SCHEMBL8916879 | 0.74 | RAB9A (0.60) | SMN1; SMN2ALDH1A1HSD17B10LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616581-A | BACTERICIDES | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| US-5504082-A | BACTERICIDE FOR HELICOBACTER, ANTIULCER AGENT, GASTRIC ACIDSUPPRESSOR | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0644191-A1 | PYRIDINE COMPOUND AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |