Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | APAF1 | O14727 | 3/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29272751 | 0.86 | BRD4 (0.39) | BRD4ELANEKMT2AMEN1MAPT | |
| SCHEMBL56435 | 0.75 | ELANE (0.67) | RAB9APOLBAPAF1ELANEKMT2A | |
| SCHEMBL14028213 | 0.74 | PDE4A (0.49) | BRD4SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL8907372 | 0.71 | POLB (0.67) | RAB9APOLBAPAF1PAX8KMT2A | |
| SCHEMBL9269288 | 0.71 | ELANE (0.61) | RAB9APOLBAPAF1ELANEKMT2A | |
| SCHEMBL7818677 | 0.70 | CYP1A2 (0.33) | BRD4SMN1; SMN2ALDH1A1KDM4ELMNA | |
| Anthraquinone SCHEMBL28260408 | 0.69 | MEN1 (0.92) | RAB9APOLBAPAF1ELANEKMT2A | |
| Marcanin A SCHEMBL29923975 | 0.69 | RAB9A (0.47) | RAB9APOLBAPAF1PAX8ELANE | |
| SCHEMBL8920440 | 0.68 | RAB9A (0.56) | RAB9APOLBAPAF1PAX8ELANE | |
| Anthraquinone SCHEMBL10786325 | 0.68 | KMT2A (0.67) | RAB9APOLBAPAF1ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605905-A | DIAZAQUINOMICIN ANALOGS | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1997-02-25 | — | — | US | disclosed |
| EP-0574195-A1 | Antitumoral aza- and diazaanthracenes | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 1993-12-15 | — | — | EP | disclosed |