Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8917258 | 0.89 | PNMT (0.54) | PNMTTAAR1TBXA2R | |
| Hydrochloric Acid SCHEMBL5363324 | 0.83 | PNMT (0.42) | PNMT | |
| SCHEMBL28025368 | 0.82 | HTR2A (0.32) | PNMT | |
| Hydrochloric Acid SCHEMBL5358974 | 0.80 | PNMT (0.42) | PNMT | |
| Hydrochloric Acid SCHEMBL5366069 | 0.75 | PNMT (0.42) | PNMT | |
| SCHEMBL7938898 | 0.74 | TSHR (0.43) | — | |
| SCHEMBL8857192 | 0.71 | PNMT (0.44) | PNMT | |
| SCHEMBL7605038 | 0.70 | PNMT (0.43) | PNMT | |
| SCHEMBL18983055 | 0.70 | HTR5A (0.31) | — | |
| Hydrochloric Acid SCHEMBL8918032 | 0.68 | MAP3K9 (0.40) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668230-A | METALLOCENE WITH ETHYLENE BRIDGED FLUORENE UNITS, ALUMOXANE COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-16 | — | — | US | claimed |