Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 10/20 | 0.34 |
| ▸ | TP53 | P04637 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916889 | 0.82 | SMN1; SMN2 (0.36) | MAPTTP53LMNAALDH1A1THRB | |
| SCHEMBL8917269 | 0.76 | ADRB1 (0.34) | ADRB1MAPTTP53LMNAALDH1A1 | |
| SCHEMBL1447600 | 0.72 | ADRB1 (0.62) | ADRB1MAPTLMNAALDH1A1THRB | |
| SCHEMBL217611 | 0.71 | ADRB1 (0.60) | ADRB1LMNAALDH1A1RECQLKMT2A | |
| SCHEMBL8991823 | 0.70 | DRD2 (0.35) | CTSGCMA1 | |
| SCHEMBL8918038 | 0.70 | ADORA2A (0.37) | ADRB1MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL8919052 | 0.70 | MAPT (0.58) | MAPTTP53LMNAALDH1A1RECQL | |
| SCHEMBL8917044 | 0.70 | MAPT (0.48) | MAPTTP53LMNAALDH1A1RECQL | |
| SCHEMBL1448499 | 0.69 | KDM4E (0.51) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL8404359 | 0.68 | CTSG (0.37) | MAPTALDH1A1CTSGCMA1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |