Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.46 |
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917865 | 0.90 | MAPT (0.38) | ACHEBCHEMCHR1TP53MAPT | |
| Hydrochloric Acid SCHEMBL8918152 | 0.87 | ACHE (0.39) | ACHEBCHEMCHR1TP53MAPT | |
| SCHEMBL8917705 | 0.85 | DRD2 (0.52) | MCHR1TP53MAPTGAAPOLB | |
| SCHEMBL8919111 | 0.83 | DRD2 (0.51) | — | |
| Hydrochloric Acid SCHEMBL8917305 | 0.83 | ACHE (0.36) | ACHEBCHEMCHR1TP53MAPT | |
| SCHEMBL8916565 | 0.81 | MAOA (0.41) | MCHR1TP53MAPTPOLBKDM4E | |
| SCHEMBL8916433 | 0.80 | TP53 (0.40) | MCHR1TP53MAPTGAAPOLB | |
| Oxalic Acid SCHEMBL8916497 | 0.80 | DRD2 (0.45) | — | |
| SCHEMBL8916426 | 0.79 | MAPT (0.40) | MCHR1TP53MAPTGAAPOLB | |
| SCHEMBL8916930 | 0.78 | SLC6A4 (0.52) | MCHR1TP53MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |