Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917892 | 0.94 | MAOA (0.41) | MAOAMAOBMAPTTHRBP2RX3 | |
| Hydrochloric Acid SCHEMBL8918152 | 0.86 | ACHE (0.39) | MAPTTHRBP2RX3MEN1ALDH1A1 | |
| SCHEMBL8917035 | 0.81 | ACHE (0.46) | MAPTMEN1ALDH1A1KMT2APOLB | |
| SCHEMBL8917865 | 0.79 | MAPT (0.38) | MAPTMEN1KMT2APOLBTP53 | |
| SCHEMBL8920505 | 0.77 | CTSS (0.39) | MAPTTHRBP2RX3MEN1ALDH1A1 | |
| SCHEMBL8917017 | 0.77 | HTR2A (0.46) | — | |
| SCHEMBL8917705 | 0.75 | DRD2 (0.52) | MAPTTHRBMEN1ALDH1A1KMT2A | |
| SCHEMBL8916426 | 0.73 | MAPT (0.40) | MAPTTHRBMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL8917305 | 0.73 | ACHE (0.36) | MAPTTP53MCHR1SMN1; SMN2 | |
| SCHEMBL8916977 | 0.72 | CTSS (0.37) | MAPTPOLBTP53MCHR1BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |