Hydrochloric Acid

Hydrochloric Acid

SCHEMBL8917797

[Cl-].[Cl-].[Zr+2].c1ccc(Cc2ccc(CCc3cccc4c3Cc3ccccc3-4)c3c2-c2ccccc2C3)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.31
CHRM1 known ✓ P11229 1/20 0.31
CHRM3 known ✓ P20309 1/20 0.31
PNMT P11086 1/20 0.49
DRD2 P14416 2/20 0.40
DRD4 P21917 2/20 0.40
DRD3 P35462 2/20 0.40
MAP3K9 P80192 1/20 0.36
MAP3K11 Q16584 1/20 0.36
ELANE P08246 3/20 0.35
CTSG P08311 1/20 0.35
HTR2A P28223 1/20 0.33
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
APAF1 O14727 2/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
GAA P10253 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8918032 0.93 MAP3K9 (0.40) PNMTDRD2DRD4DRD3MAP3K9
SCHEMBL8151881 0.83 PNMT (0.64) PNMTDRD2DRD4DRD3ELANE
Hydrochloric Acid SCHEMBL5348072 0.83 PNMT (0.68) PNMTDRD2DRD4DRD3MAP3K9
SCHEMBL27755193 0.81 PNMT (0.62) PNMTDRD2DRD4DRD3RAB9A
Hydrochloric Acid SCHEMBL8917258 0.80 PNMT (0.54) PNMTDRD2DRD4DRD3MAP3K9
SCHEMBL8917078 0.80 DRD2 (0.46) PNMTDRD2DRD4DRD3ELANE
Hydrochloric Acid SCHEMBL5357887 0.80 PNMT (0.68) PNMTDRD2DRD4DRD3MAP3K9
Hydrochloric Acid SCHEMBL9245137 0.80 PNMT (0.68) PNMTDRD2DRD4DRD3MAP3K9
Hydrochloric Acid SCHEMBL5357566 0.80 PNMT (0.68) PNMTDRD2DRD4DRD3MAP3K9
SCHEMBL5366733 0.80 PNMT (0.72) PNMTDRD2DRD4DRD3MAP3K9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5668230-A METALLOCENE WITH ETHYLENE BRIDGED FLUORENE UNITS, ALUMOXANE COCATALYST PHILLIPS PETROLEUM COMPANY (US) 1997-09-16 US claimed