Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918420 | 0.82 | PTPN1 (0.40) | PTPN1KMT2ADRD2SLC6A4HRH4 | |
| SCHEMBL8920622 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KMT2ADRD2SLC6A4HRH4 | |
| SCHEMBL8916173 | 0.82 | PTPN1 (0.40) | PTPN1ALDH1A1KMT2ADRD2SLC6A4 | |
| SCHEMBL29688867 | 0.82 | KCNH2 (0.45) | PTPN1KMT2ASLC6A4KCNH2 | |
| SCHEMBL4491304 | 0.82 | KCNH2 (0.45) | PTPN1KMT2ASLC6A4KCNH2 | |
| SCHEMBL6125296 | 0.79 | DRD2 (0.48) | ALDH1A1DRD2SLC6A4HRH4HTR2A | |
| SCHEMBL8918815 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2AHSD17B10KDM4E | |
| SCHEMBL7700928 | 0.78 | DRD2 (0.55) | ALDH1A1DRD2SLC6A4HTR2ADRD3 | |
| SCHEMBL8920208 | 0.77 | PTPN1 (0.43) | PTPN1ALDH1A1DRD2SLC6A4 | |
| SCHEMBL8917953 | 0.75 | PSMB8 (0.40) | ALDH1A1DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |