Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 4/20 | 0.35 |
| ▸ | PIM1 | P11309 | 4/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 7/20 | 0.34 |
| ▸ | MAOA | P21397 | 6/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917162 | 0.82 | PTPN1 (0.40) | PTPN1ALDH1A1HTTDRD2SLC6A4 | |
| SCHEMBL8918420 | 0.82 | PTPN1 (0.40) | PTPN1HTTDRD2SLC6A4KMT2A | |
| SCHEMBL8920622 | 0.82 | ALDH1A1 (0.39) | ALDH1A1DRD2SLC6A4MAOBMAOA | |
| SCHEMBL8918815 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HTTMAOBMAOAMEN1 | |
| SCHEMBL7700928 | 0.78 | DRD2 (0.55) | ALDH1A1DRD2SLC6A4SMN1; SMN2 | |
| SCHEMBL8917953 | 0.75 | PSMB8 (0.40) | ALDH1A1DRD2SLC6A4 | |
| SCHEMBL12597179 | 0.73 | STS (0.44) | PTPN1ALDH1A1HTTDRD2SLC6A4 | |
| SCHEMBL8917923 | 0.73 | MAPT (0.39) | ALDH1A1HTTDRD2SLC6A4MEN1 | |
| SCHEMBL8917899 | 0.73 | CYP11B1 (0.40) | DRD2SLC6A4 | |
| SCHEMBL8920208 | 0.71 | PTPN1 (0.43) | PTPN1ALDH1A1DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |