Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 5/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8917460 | 0.81 | HTR2C (0.41) | MAOB | |
| SCHEMBL8916199 | 0.73 | KMT2A (0.39) | — | |
| SCHEMBL8917162 | 0.73 | PTPN1 (0.40) | AHR | |
| SCHEMBL8915744 | 0.71 | ADORA2A (0.38) | — | |
| SCHEMBL8920208 | 0.71 | PTPN1 (0.43) | — | |
| SCHEMBL7700928 | 0.68 | DRD2 (0.55) | — | |
| SCHEMBL8917953 | 0.66 | PSMB8 (0.40) | — | |
| SCHEMBL10139329 | 0.64 | AHR (0.49) | MAOBAHR | |
| SCHEMBL3962246 | 0.64 | TP53 (0.48) | — | |
| SCHEMBL8916173 | 0.64 | PTPN1 (0.40) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |