SCHEMBL891744

SCHEMBL891744

CCC/C=C\COC(C)=O

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
LMNA P02545 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALOX15 P16050 1/20 0.42
PTPN1 P18031 1/20 0.37
TSHR P16473 1/20 0.37
PRKCA P17252 1/20 0.36
PTGS1 P23219 1/20 0.35
FAAH O00519 2/20 0.34
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112504 1.00 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10ALOX15PTPN1
SCHEMBL112505 1.00 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10ALOX15PTPN1
Acetic Acid SCHEMBL28335241 0.96 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10ALOX15PTPN1
Acetic Acid SCHEMBL28335240 0.96 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10ALOX15PTPN1
SCHEMBL19693196 0.92 PTPN1 (0.47) LMNAHSD17B10ALOX15PTPN1PRKCA
SCHEMBL19693195 0.92 PTPN1 (0.47) LMNAHSD17B10ALOX15PTPN1PRKCA
SCHEMBL19693197 0.92 PTPN1 (0.47) LMNAHSD17B10ALOX15PTPN1PRKCA
SCHEMBL19693193 0.92 PTPN1 (0.47) LMNAHSD17B10ALOX15PTPN1PRKCA
SCHEMBL14296530 0.88 ALDH1A1 (0.47) ALDH1A1LMNAHSD17B10ALOX15PTPN1
SCHEMBL31508640 0.88 ALDH1A1 (0.47) ALDH1A1LMNAHSD17B10ALOX15PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 EP claimed
EP-4565194-A1 ODOR AND COLORANT STABILIZED COMPOSITIONS Symrise AG (DE) 2025-06-11 EP claimed
US-20250163006-A1 New Coolants, and Preparations Containing Same SYMRISE AG (DE) 2025-05-22 US claimed
CN-119924491-A Flavoring composition with balanced taste characteristics 西姆莱斯有限公司 2025-05-06 CN claimed
CN-119744164-A Odor and colorant stable compositions 西姆莱斯股份公司 2025-04-01 CN claimed
WO-2025026525-A1 HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS SYMRISE AG (DE) 2025-02-06 WO claimed
US-20250040580-A1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-02-06 US claimed
EP-4469439-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-12-04 EP claimed
EP-3689324-B1 NEW COOLING AGENTS AND PREPARATIONS COMPRISING THEM SYMRISE AG (DE) 2024-11-20 EP claimed
CN-110833069-A Attractant for Chouioia cunea Yang and application thereof 南京林业大学 2020-02-25 CN claimed
EP-2446751-B1 Heat-stable aroma particle with high impact SYMRISE AG (DE) 2018-01-10 EP claimed
EP-2742983-B1 Method for isolating fragrance and flavour compounds SYMRISE AG (DE) 2017-08-23 EP claimed
US-9005688-B2 Thermally stable high impact flavoring particles SYMRISE AG (DE) 2015-04-14 US claimed
EP-2742983-A1 Method for isolating fragrance and flavour compounds Symrise AG (DE) 2014-06-18 EP claimed
EP-2559346-B1 Oleanene-type triterpene glycosides as masking agents SYMRISE AG (DE) 2014-03-26 EP claimed
WO-2013023891-A1 OLEANENE-TYPE TRITERPENE GLYCOSIDES AS MASKING AGENTS SYMRISE AG (DE) 2013-02-21 WO claimed
EP-2559346-A1 Oleanene-type triterpene glycosides as masking agents Symrise AG (DE) 2013-02-20 EP claimed
US-20120107477-A1 THERMALLY STABLE HIGH IMPACT FLAVORING PARTICLES SYMRISE AG (DE) 2012-05-03 US claimed
US-20090197939-A1 METHODS OF TREATING SKIN WITH AROMATIC SKIN-ACTIVE INGREDIENTS MARY KAY INC. (US) 2009-08-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12568998-B2 Flavouring composition with balanced taste profile TAS2R20, TAS2R50, TAS2R40 ALDH1A1 1337/4885LMNA 2789/4885HSD17B10 183/4885
US-20090197939-A1 METHODS OF TREATING SKIN WITH AROMATIC SKIN-ACTIVE INGREDIENTS MMP8, LOX, TYR ALDH1A1 236/4885LMNA 846/4885HSD17B10 761/4885
US-20250163006-A1 New Coolants, and Preparations Containing Same TTR, TAS2R5, TAS2R50 ALDH1A1 811/4885LMNA 3005/4885HSD17B10 1631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.