Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917637 | 0.86 | CACNB4 (0.54) | HTTHSD17B10KDM4ERAB9AAR | |
| SCHEMBL8974906 | 0.84 | HSD17B10 (0.68) | HTTHSD17B10ADRA2AADORA2AKDM4E | |
| SCHEMBL8975579 | 0.81 | ALDH1A1 (0.55) | HTTHSD17B10ADRA2AADORA2AKDM4E | |
| SCHEMBL8918356 | 0.76 | ALDH1A1 (0.55) | HTTHSD17B10ADRA2AADORA2AIKBKB | |
| SCHEMBL13914270 | 0.75 | IKBKB (0.50) | HTTHSD17B10ADRA2AADORA2AIKBKB | |
| SCHEMBL6137173 | 0.75 | AR (0.57) | HTTKDM4ERAB9AARALDH1A1 | |
| SCHEMBL6461123 | 0.75 | KDM4E (0.60) | HTTHSD17B10ADRA2AADORA2AIKBKB | |
| SCHEMBL13913807 | 0.73 | ADORA1 (0.48) | HTTHSD17B10ADORA2AIKBKBKDM4E | |
| SCHEMBL13913805 | 0.72 | ADORA1 (0.66) | HSD17B10ADORA2AKDM4ERXFP1ALDH1A1 | |
| SCHEMBL6252188 | 0.72 | IKBKB (0.67) | HTTHSD17B10ADORA2AIKBKBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705820-A1 | 6-Amino-nicotinic acid derivatives and their use as selective K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |