Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917192 | 0.89 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8918613 | 0.87 | GAA (0.68) | ALDH1A1L3MBTL1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8974906 | 0.85 | HSD17B10 (0.68) | ALDH1A1L3MBTL1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL8917637 | 0.85 | CACNB4 (0.54) | ALDH1A1L3MBTL1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10379148 | 0.84 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL14616739 | 0.81 | SMN1; SMN2 (0.73) | ALDH1A1L3MBTL1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL15976546 | 0.80 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL22866595 | 0.79 | ADORA3 (0.58) | ALDH1A1L3MBTL1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL29662041 | 0.79 | ADORA3 (0.58) | ALDH1A1L3MBTL1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL1195232 | 0.77 | MAPT (0.68) | ALDH1A1L3MBTL1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | claimed |
| EP-0705820-A1 | 6-Amino-nicotinic acid derivatives and their use as selective K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | claimed |
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0705820-A1 | 6-Amino-nicotinic acid derivatives and their use as selective K-channel modulators | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |