Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.42 |
| ▸ | CPS1 | P31327 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672823 | 0.81 | CES2 (0.50) | HSD11B1KMT2AALDH1A1CPS1MEN1 | |
| SCHEMBL4674606 | 0.75 | KEAP1 (0.51) | HSD11B1KMT2APIN1ALDH1A1MEN1 | |
| SCHEMBL9820662 | 0.74 | KDM4E (0.56) | KMT2ALMNAPIN1ALDH1A1HTT | |
| SCHEMBL27709578 | 0.73 | NPC1 (0.51) | KMT2ALMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL4673461 | 0.73 | GAA (0.39) | HSD11B1KMT2AALDH1A1HTTMEN1 | |
| SCHEMBL8280196 | 0.72 | HSD11B1 (0.44) | HSD11B1LMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL30675620 | 0.72 | ALDH1A1 (0.62) | LMNASMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL1020142 | 0.72 | SMN1; SMN2 (0.49) | KMT2ALMNASMN1; SMN2ALDH1A1HTT | |
| SCHEMBL927338 | 0.72 | ALDH1A1 (0.62) | LMNASMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL30134039 | 0.72 | SMN1; SMN2 (0.49) | KMT2ALMNASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |