Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918420 | 0.88 | PTPN1 (0.40) | CYP11B1CYP11B2CYP19A1CYP17A1DRD2 | |
| SCHEMBL8917923 | 0.82 | MAPT (0.39) | DRD2SLC6A4STSHTR2ADRD3 | |
| SCHEMBL6811575 | 0.82 | SLC6A2 (0.44) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL6895884 | 0.81 | SLC6A2 (0.43) | SLC6A4 | |
| SCHEMBL21525054 | 0.78 | CHRNB2 (0.47) | CYP11B1CYP11B2CYP19A1CYP17A1AVPR2 | |
| SCHEMBL7700928 | 0.78 | DRD2 (0.55) | DRD2SLC6A4HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL28261072 | 0.77 | CHRNB2 (0.46) | CYP11B1CYP11B2CYP19A1CYP17A1AVPR2 | |
| SCHEMBL8917953 | 0.75 | PSMB8 (0.40) | CYP17A1DRD2SLC6A4STS | |
| SCHEMBL7700143 | 0.74 | CTSS (0.49) | DRD2SLC6A4CTSSHTR1FHTR2A | |
| SCHEMBL8916173 | 0.73 | PTPN1 (0.40) | DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |