SCHEMBL8917949

SCHEMBL8917949

CC(C)CC(C)COc1ccc2c(c1)C(=N)NC21OC(C)O1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.32
CREBBP Q92793 1/20 0.32
PDK2 Q15119 1/20 0.32
AAK1 Q2M2I8 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8919366 0.92 PDK2 (0.34) BRD4CREBBPPDK2AAK1
SCHEMBL8919289 0.82 ALDH1A1 (0.39) PDK2
SCHEMBL7826144 0.80 PDK2 (0.34) PDK2AAK1
SCHEMBL8920374 0.80 KMT2A (0.36) PDK2
SCHEMBL8919249 0.80 MEN1 (0.36) PDK2
SCHEMBL8918904 0.78 ACHE (0.36) PDK2
SCHEMBL8921444 0.77 PDK2 (0.38) PDK2
SCHEMBL7835436 0.77 PDK2 (0.33) PDK2AAK1
SCHEMBL8920291 0.76
SCHEMBL8919145 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed