SCHEMBL8918904

SCHEMBL8918904

COc1ccc2c(c1)C(=N)NC21OC(C)O1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
ALDH1A1 P00352 3/20 0.35
PDK2 Q15119 1/20 0.34
AKR1A1 P14550 1/20 0.34
AKR1B1 P15121 1/20 0.34
NQO1 P15559 2/20 0.33
POR P16435 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
TSHR P16473 1/20 0.33
GFER P55789 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA7 P43166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8920935 0.89 ALDH1A1 (0.35) ACHEALDH1A1PDK2AKR1A1AKR1B1
SCHEMBL8919289 0.85 ALDH1A1 (0.39) ALDH1A1PDK2NQO1KDM4EMEN1
SCHEMBL8921050 0.84 MAOB (0.40) ACHEPDK2MAPTTSHR
SCHEMBL8919249 0.83 MEN1 (0.36) ALDH1A1PDK2MEN1MAPTKMT2A
SCHEMBL8920374 0.83 KMT2A (0.36) ALDH1A1PDK2KDM4EMEN1MAPT
SCHEMBL8918901 0.81 ALDH1A1 (0.39) ACHEALDH1A1PDK2AKR1A1AKR1B1
SCHEMBL8920313 0.81 ACHE (0.32) ACHEALDH1A1KDM4EMAPTHSD17B10
SCHEMBL8921444 0.80 PDK2 (0.38) PDK2KDM4EMAPTTSHRHTR2A
SCHEMBL8918851 0.79 PPOX (0.32)
SCHEMBL8917949 0.78 BRD4 (0.32) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed