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SCHEMBL9352000

SCHEMBL9352000

CCCCCCCCON1C(C)(C)CC(N(C(=O)NCCCCCCNC(=O)N(C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)C2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)CC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ EPHX2 P34913 10/20 0.40
▸ EPHX1 P07099 5/20 0.38
▸ ACHE P22303 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9351971 0.88 EPHX2 (0.35) EPHX2EPHX1ACHE
SCHEMBL9351981 0.82 EPHX2 (0.36) EPHX2
SCHEMBL9351996 0.80 TSHR (0.43) EPHX2
SCHEMBL9226072 0.79 HCAR2 (0.35) EPHX2
SCHEMBL2947525 0.78 SMN1; SMN2 (0.41) EPHX2EPHX1
SCHEMBL2462031 0.77 DGKA (0.34) EPHX2
SCHEMBL2461222 0.77 EPHX2 (0.30) EPHX2
SCHEMBL8917970 0.77 KDM5A (0.36) EPHX2
SCHEMBL8917966 0.76 NAAA (0.40) EPHX2
SCHEMBL17888055 0.76 EPHX1 (0.51) EPHX2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389434-B1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA GEIGY AG (CH) 1994-09-21 — — EP disclosed
US-5015683-A Acting radiation resistance CIBA-GEIGY CORPORATION (US) 1991-05-14 — — US disclosed
EP-0389434-A1 Bis(1-hydrocarbyloxy-2,2,6,6-tetramethylpiperidin-4-yl)-amine Derivatives and Stabilized compositions CIBA-GEIGY AG (CH) 1990-09-26 — — EP disclosed