Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917631 | 0.72 | CDC7 (0.35) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8917302 | 0.71 | ALDH1A1 (0.52) | ALDH1A1HTT | |
| SCHEMBL8916133 | 0.68 | NOTUM (0.33) | ALDH1A1USP2MAPK1HTTTDP1 | |
| SCHEMBL8917337 | 0.65 | ALDH1A1 (0.42) | ALDH1A1MAPK1 | |
| SCHEMBL8916102 | 0.62 | MCHR1 (0.37) | ALDH1A1 | |
| SCHEMBL8917854 | 0.61 | PARP1 (0.35) | ALDH1A1 | |
| SCHEMBL17713734 | 0.60 | CDC7 (0.31) | ALDH1A1USP2MAPK1HTTTDP1 | |
| SCHEMBL21441660 | 0.58 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL8991820 | 0.57 | RYR2 (0.33) | — | |
| SCHEMBL8917048 | 0.56 | MEN1 (0.46) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |