Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | ESRRG | P62508 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839159 | 0.94 | LTA4H (0.52) | LTA4HKCNH2ESRRGLSSHTR6 | |
| SCHEMBL8845637 | 0.84 | OPRM1 (0.44) | LTA4HSMN1; SMN2MAPTNPC1TP53 | |
| SCHEMBL8918082 | 0.83 | LTA4H (0.55) | LTA4HKCNH2ESRRGLSSHTR6 | |
| SCHEMBL9839254 | 0.83 | OPRM1 (0.46) | LTA4HMAPTNPC1OPRM1RAB9A | |
| SCHEMBL9839431 | 0.81 | BCHE (0.46) | SMN1; SMN2LMNAPOLBMEN1NPC1 | |
| SCHEMBL9838128 | 0.79 | BCHE (0.46) | SMN1; SMN2LMNAPOLBMEN1NPC1 | |
| SCHEMBL8915518 | 0.78 | LTA4H (0.55) | LTA4HKCNH2ESRRGLSSHTR6 | |
| SCHEMBL9838108 | 0.78 | LTA4H (0.43) | LTA4HMAPTNPC1TP53OPRM1 | |
| SCHEMBL9837820 | 0.77 | CA12 (0.42) | SMN1; SMN2MAPTKDM4EMEN1NPC1 | |
| SCHEMBL8845495 | 0.75 | LTA4H (0.58) | LTA4HKCNH2ESRRGLSSHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |