Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839168 | 0.94 | LTA4H (0.49) | LTA4HLSSHTR6LMNAHRH3 | |
| SCHEMBL8918082 | 0.86 | LTA4H (0.55) | LTA4HLSSHTR6LMNAHRH3 | |
| SCHEMBL8915518 | 0.84 | LTA4H (0.55) | LTA4HLSSHTR6LMNAHRH3 | |
| SCHEMBL8915871 | 0.78 | LTA4H (0.58) | LTA4HLSSHTR6LMNAHRH3 | |
| SCHEMBL8845495 | 0.78 | LTA4H (0.58) | LTA4HLSSHTR6LMNAHRH3 | |
| SCHEMBL9839254 | 0.77 | OPRM1 (0.46) | LTA4HMAPTNPC1OPRM1RAB9A | |
| Hydrochloric Acid SCHEMBL10574784 | 0.77 | LTA4H (0.56) | LTA4HLSSHTR6LMNAHRH3 | |
| SCHEMBL9839855 | 0.76 | MAOB (0.41) | LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8916213 | 0.75 | CYP2D6 (0.53) | LTA4HHTR6HRH3ESR1CYP2D6 | |
| SCHEMBL8845637 | 0.75 | OPRM1 (0.44) | LTA4HMAPTNPC1TP53OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |