Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843536 | 0.87 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL7839858 | 0.84 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL7843538 | 0.81 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL8918780 | 0.80 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL7841792 | 0.76 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7832068 | 0.76 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL7839793 | 0.74 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL7847052 | 0.74 | PTGDR2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7833914 | 0.74 | PTGS2 (0.68) | PTGS2PTGS1 | |
| SCHEMBL7843097 | 0.72 | PTGS2 (0.67) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668161-A | Substituted thiazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 1997-09-16 | — | — | US | disclosed |