Benzotriazole

Benzotriazole

SCHEMBL8919418

O=[N+]([O-])c1ccc2[nH]cnc2c1.c1ccc2[nH]nnc2c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.56
NAMPT P43490 1/20 0.56
XDH P47989 1/20 0.56
ALDH1A1 P00352 2/20 0.45
PARP1 P09874 1/20 0.45
MAPT P10636 6/20 0.41
HPGD P15428 1/20 0.40
CTSV O60911 1/20 0.39
CTSL P07711 1/20 0.39
POLB P06746 2/20 0.39
MAOB P27338 1/20 0.39
NOS1 P29475 1/20 0.39
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29923659 0.84 CYP3A4 (0.77) CYP3A4NAMPTXDHALDH1A1PARP1
SCHEMBL271340 0.84 CYP3A4 (0.77) CYP3A4NAMPTXDHALDH1A1PARP1
Silver SCHEMBL11230934 0.82 CYP3A4 (0.75) CYP3A4NAMPTXDHALDH1A1PARP1
SCHEMBL8425555 0.82 CYP3A4 (0.75) CYP3A4NAMPTXDHALDH1A1PARP1
Benzimidazole SCHEMBL4886532 0.82 SMN1; SMN2 (0.39) CYP3A4NAMPTXDHALDH1A1PARP1
SCHEMBL238008 0.81 MAPT (0.51) CYP3A4NAMPTXDHALDH1A1MAPT
Nitric Acid SCHEMBL4907401 0.80 CYP3A4 (0.71) CYP3A4NAMPTXDHALDH1A1PARP1
SCHEMBL8424660 0.79 MAPT (0.50) CYP3A4NAMPTXDHALDH1A1MAPT
Silver SCHEMBL9173415 0.79 MAPT (0.50) CYP3A4NAMPTXDHALDH1A1MAPT
Nitrobenzene SCHEMBL29202953 0.78 ALDH1A1 (0.53) ALDH1A1MAPTHPGDMMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5599648-A TRANSFERRING AN POLYMERIC OVERCOATINGS BY LAMINATING THE OVERCOATINGS, LIGHT EXPOSURE TO CROSSLINK, PEELING OFF CANON KABUSHIKI KAISHA (JP) 1997-02-04 US disclosed
EP-0471483-A1 Surface reforming method, process for production of printing plate, printing plate and printing process CANON KABUSHIKI KAISHA (JP) 1992-02-19 EP disclosed