Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12388226 | 0.75 | MAPT (0.56) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL719005 | 0.73 | KDM4E (0.57) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL1810653 | 0.73 | RAB9A (0.47) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL8396995 | 0.72 | NPC1 (0.72) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL2169866 | 0.72 | MAPT (0.61) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL8920364 | 0.70 | ENPP2 (0.57) | MEN1KMT2AHDAC1HDAC3 | |
| SCHEMBL8920494 | 0.70 | ENPP2 (0.57) | MEN1KMT2AHDAC1HDAC3 | |
| SCHEMBL8921731 | 0.70 | ENPP2 (0.57) | MEN1KMT2AHDAC1HDAC3 | |
| SCHEMBL8920548 | 0.70 | ENPP2 (0.57) | MEN1KMT2AHDAC1HDAC3 | |
| SCHEMBL8921079 | 0.70 | ENPP2 (0.57) | MEN1KMT2AHDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670493-A | ANGIOGENESIS INHIBITORS | ADIR ET COMPAGNIE (FR) | 1997-09-23 | — | — | US | disclosed |