SCHEMBL8920932

SCHEMBL8920932

COc1ccc2c(c1)C1(NC2=N)OCCO1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 2/20 0.38
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.35
MEN1 O00255 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
TDP2 O95551 1/20 0.35
METAP1 P53582 1/20 0.35
PDK2 Q15119 1/20 0.35
LRRK2 Q5S007 1/20 0.34
TSHR P16473 1/20 0.34
GFER P55789 1/20 0.34
HSD17B10 Q99714 1/20 0.34
AKR1B1 P15121 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33
TP53 P04637 1/20 0.33
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8918901 0.88 ALDH1A1 (0.39) PDE7AALDH1A1KDM4EMEN1MAPT
SCHEMBL8918297 0.85 PDK2 (0.39) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL8918850 0.82 MAOA (0.46) MAPTPDK2AKR1B1
SCHEMBL8920935 0.81 ALDH1A1 (0.35) PDE7AALDH1A1KDM4EMEN1MAPT
SCHEMBL8918856 0.79 PDK2 (0.44) PDK2TSHRPDE3BPDE3A
SCHEMBL8920969 0.77 AKR1A1 (0.37) PDE7ATDP2PDK2AKR1B1
SCHEMBL7817179 0.76 MEN1 (0.40) PDE7AALDH1A1KDM4EMEN1MAPT
SCHEMBL8919281 0.73 ALDH1A1 (0.40) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL8918879 0.73 PDE7A (0.39) PDE7AALDH1A1KDM4EMEN1MAPT
SCHEMBL7816522 0.73 MEN1 (0.34) ALDH1A1KDM4EMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691272-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1997-11-25 US disclosed
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed
EP-0679640-A1 Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, Inc. (JP) 1995-11-02 EP disclosed