Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | MMP13 | P45452 | 4/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920514 | 1.00 | CTSL (0.53) | CTSLMAPTMEN1KMT2APLAU | |
| SCHEMBL8920959 | 0.81 | METAP2 (0.52) | MAPTMEN1KMT2APLAUHPN | |
| SCHEMBL8458621 | 0.81 | METAP2 (0.50) | METAP2 | |
| SCHEMBL30988968 | 0.78 | GAA (0.55) | CTSLKMT2AMMP2MMP9MMP13 | |
| SCHEMBL28554116 | 0.78 | GAA (0.55) | CTSLKMT2AMMP2MMP9MMP13 | |
| SCHEMBL2238427 | 0.77 | METAP2 (0.53) | METAP2 | |
| SCHEMBL16312116 | 0.77 | TDP1 (0.54) | MAPTMEN1KMT2AMMP2MMP9 | |
| SCHEMBL7835649 | 0.76 | GAA (0.52) | CTSLKMT2APLAUHPNMMP2 | |
| SCHEMBL14011605 | 0.76 | GAA (0.52) | CTSLKMT2APLAUHPNMMP2 | |
| SCHEMBL4040020 | 0.76 | GAA (0.52) | CTSLKMT2APLAUHPNMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684137-A | TECHNETIUM AND RHENIUM LABELS FOR LIGANDS AND PROTEINS | NEORX CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5252721-A | S3 N chelating compounds | NEORX CORPORATION (US) | 1993-10-12 | — | — | US | disclosed |