Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238552 | 0.84 | METAP2 (0.60) | METAP2KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7323491 | 0.84 | METAP2 (0.60) | METAP2KMT2AMEN1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7323488 | 0.83 | METAP2 (0.59) | METAP2ALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL3366424 | 0.83 | METAP2 (0.59) | METAP2ALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL8920506 | 0.81 | CTSL (0.53) | METAP2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8920514 | 0.81 | CTSL (0.53) | METAP2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL10519231 | 0.81 | ALDH1A1 (0.49) | METAP2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL27538430 | 0.81 | LMNA (0.47) | METAP2KMT2AMEN1MAPTBCHE | |
| SCHEMBL4141148 | 0.75 | METAP2 (0.52) | METAP2MAPTHTTGAAL3MBTL1 | |
| SCHEMBL1839764 | 0.75 | METAP2 (0.52) | METAP2MAPTHTTGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684137-A | TECHNETIUM AND RHENIUM LABELS FOR LIGANDS AND PROTEINS | NEORX CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5252721-A | S3 N chelating compounds | NEORX CORPORATION (US) | 1993-10-12 | — | — | US | disclosed |