Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | PDE8A | O60658 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE9A | O76083 | 1/20 | 0.35 |
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | PDE6A | P16499 | 1/20 | 0.35 |
| ▸ | PDE6G | P18545 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE6B | P35913 | 1/20 | 0.35 |
| ▸ | PDE6C | P51160 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691683 | 0.81 | NPSR1 (0.40) | KDM4EALDH1A1PDE3ADAOADORA3 | |
| SCHEMBL8688652 | 0.79 | OPRM1 (0.40) | KDM4EALDH1A1PDE5A | |
| SCHEMBL8687317 | 0.78 | HSD11B1 (0.35) | DAO | |
| SCHEMBL8977216 | 0.78 | MGLL (0.44) | ALDH1A1DAONPEPPSHCAR1 | |
| SCHEMBL8686392 | 0.76 | EPHX2 (0.49) | — | |
| SCHEMBL8686853 | 0.72 | DAO (0.35) | KDM4EALDH1A1DAOP2RX7ADORA3 | |
| SCHEMBL18504489 | 0.72 | MGLL (0.36) | ALDH1A1DAONPEPPSHTR1AHCAR1 | |
| SCHEMBL8686617 | 0.69 | RAB9A (0.45) | KDM4EALDH1A1 | |
| SCHEMBL8686970 | 0.69 | LMNA (0.35) | DAO | |
| SCHEMBL8686860 | 0.69 | KDM4E (0.36) | KDM4EALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641727-A | Herbicidal 1-pyridyltetrazolinones | NIHON BAYER AGROCHEM K.K. (JP) | 1997-06-24 | — | — | US | disclosed |